Several of the drugs used in this study were provided by the National Institute on Drug Abuse (NIDA) Drug Supply Program.Īuthor contributions: M.V.V. Analysis for this project was performed in the UC Davis Campus Mass Spectrometry Facilities, with instrument funding provided by the NIH (1S10OD025271-01A1). Funding for the nuclear magnetic resonance spectrometers was provided by the National Science Foundation (NSF CHE-04-43516) and NIH (08P0ES 05707C). We thank the MCB Light Microscopy Imaging Facility, which is a UC Davis Campus Core Research Facility, for the use of this microscope. The Nikon High Content Analysis Spinning Disk Confocal microscope used in this study was purchased using NIH Shared Instrumentation Grant 1S10OD019980-01A1. This project used the Biological Analysis Core of the UC Davis MIND Institute Intellectual and Development Disabilities Research Center (U54 HD079125). Funding: This work was supported by funds from the National Institutes of Health (NIH) (R01GM128997 to D.E.O., R35GM133421 to J.D.M., and U01NS120820, U01NS115579, and 2R01MH101214-06 to L.T.), three NIH training grants (T32GM099608 to M.V.V., T32GM113770 to R.J.T., and T32MH112507 to H.N.S.), Human Frontier (L.T.), the Camille and Henry Dreyfus Foundation (D.E.O.), a sponsored research agreement with Delix Therapeutics (D.E.O.), and a University of California (UC) Davis Provost’s Undergraduate Fellowship (S.J.C.).

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